On one hand no exerts beneficial results on the body by playing an important role such as antibacterial antiparasital antiviral agent the lethal reaction occurs if the high amount of nitric oxide reacts with concurrently produced superoxide anions which further generate highly toxic compounds such as peroxynitrite and hydroxyl radicals. Nitric oxide emerging developments therapeutic role in disease states and health effects nitric oxide emerging developments therapeutic role in disease states and health effects library of congress cataloging in publication data contents preface chapter 1 nitric oxide in gastrointestinal and hepatic disease and health abstract 1. Nitric oxide no is a ubiquitous water soluble free radical gas which plays key role in various physiological as well as pathological processes over past decades no has emerged as a molecule of interest in carcinogenesis and tumor growth progression however there is considerable controversy . Nitric oxide therapy was started on the second day at a rate of 5 to 10 ppm her saturation improved mainly on the next day of nitric oxide therapy and it was possible to reduce the fio 2 to 60 unfortunately this effect was lost after 4 days when her general condition deteriorated and she went into cardiac arrest. Nitric oxide nitrogen monoxide is a molecule and chemical compound with chemical formula of n oin mammals including humans nitric oxide is a signaling molecule involved in many physiological and pathological processes it is a powerful vasodilator with a half life of a few seconds in the blood standard pharmaceuticals such as nitroglycerine and amyl nitrite are precursors to nitric oxide
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